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10.3390/ijms24119481 37 EntezariM.HashemiD.TaheriazamA.ZabolianA.MohammadiS.FakhriF.et al (2022)
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Animal models of muscle crush injury and tendon damage have consistently shown faster functional recovery, improved tissue architecture, and reduced scar formation when TB-500 is administered shortly after the injury
The yeast strain BJ5464-NpgA is especially engineered for PKS reconstitution and contains genetic knockouts of vacuolar proteases such as PEP4 and PBP1, as well as integration of the fungal phosphopantetheinyl transferase NpgA