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Description
The met form (Cu(II)Cu(II)) is considered as a resting enzymatic form, where Cu(II) ions are generally linked with a small ligand, such as a hydroxide ion or water molecule

127 FhrsH.BehrensC.GallienS.HeintzD.Van DorsselaerA.BraunH

Differences in stability among the human apolipoprotein E isoforms determined by the amino-terminal domain

Their studies were critical for proof-of-concept, but they were limited by their rewarming technique (convective warming on the organ surface), which was unable to reproducibly achieve the needed rates or homogeneity of heating required
