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Chronobiological Implications: Assessing the potential impacts of these peptides on circadian-regulated physiological processes

Nrf2/Trsp double-KO mice The transcription factor Nrf2 is considered as a redox switch regulating the expression of antioxidant enzymes, GSH-synthesizing enzymes, and detoxifying Phase 2 enzymes (175), while the specific selenocysteine tRNA is needed for the synthesis of selenoproteins such as GPx or Trx reductase, which reduces oxidized Trx (133) (Fig
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