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Each of these systems plays a role in ensuring that the body remains free from harmful substances

[7] High-dose methionine may antagonize the therapeutic effect of L-dopa-carbidopa regimens by increasing peripheral methylation of the drug complex, potentially reducing central bioavailability

Noel, et al

Since the definition of the disease already implies an unspecified type, no additional subcodes are needed unless the condition is secondary or drug-induced, in which case other codes may apply
