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Efficacy and Safety Assessments The primary efficacy endpoint was the change in Visual Analogue Scale (VAS) scores from baseline to the end of the study period
Lipoic acid also protected liver from oxidative stress-induced liver injury in methotrexate-treated rats through the activation of Nrf-2 pathway and other anti-inflammatory pathways (37)
An optimal range might be ~10-35 mcg/ml
