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Glutathione is the cells major antioxidant to protect the cell from damage

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The various fates of cytosolic iron are likely determined by the activity of iron transporters, such as the mitochondrial iron importers (Mitoferrin 1 and Mitoferrin 2, FIGURE 1 COMPOSITION OF THE CYTOSOLIC LABILE IRON POOL From a conceptual standpoint, the cytosol must contain a kinetically labile, metabolically accessible pool of iron so that iron can be distributed to its various sites of utilization, transport, or storage (reviewed in Attempts have been made to characterize the molecular composition of the cytosolic LIP and some progress has been made

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Using whole-genome sequencing on stool samples from children with autism and neurotypical controls, the team identified dysregulated sulfur metabolism and impaired oxidative stress detoxification at the genetic level within the bacterial communities of children with autism [7]

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