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(2003) Characterization of mammalian seleniumoproteomes, Science , 300 , 1439-1443, Gladyshev, V
Targeted deletion of Sec-tRNA [Ser]Sec ( Trsp ) gene in osteochondroprogenitor cells from embryonic stage caused the depletion of selenoproteins in skeletal systems, causing growth retardation, abnormalities in the epiphyseal growth plate, delayed endochondral ossification, and chondronecrosis, which recapitulated the major pathological features of KBD 73

Curr Eye Res 43:553565

HIF-1 has also been proposed as a regulator of NET generation by neutrophils [191], hence providing a potential mechanism by which vitamin C could downregulate NET generation by these cells [75]
