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Conditions that affect the gut, like Crohns disease or celiac disease, can damage the intestinal lining, making it difficult for B12 to pass into your bloodstream

Some chelators are responsible both for Fe excretion and may suppress the participation of free labile Fe in oxidation-reduction reactions [94]

It also keeps missed doses at a minimum

doi: 10.1016/S0140-6736(11)61452-9
