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Similarly, in LDH-deficient cells or cells treated with ( R )-GNE-140, lactyl-CoA levels were much lower than those in control cells (Fig
doi:10.3109/15376516.2013.769655 Chen CN, Brown-Borg HM, Rakoczy SG, Ferrington DA, Thompson LV (2010) Aging impairs the expression of the catalytic subunit of glutamate cysteine ligase in soleus muscle under stress

Nakanishi T, Sugawara M, Huang W, et al

Diagnosis is made by exclusion of alcohol abuse and other causes of liver disease (HBV-related hepatitis, HCV-related hepatitis, autoimmune liver diseases, polycystic ovary syndrome, drug-induced liver disease and congenital causes such as hereditary hemochromatosis, Wilsons disease, alpha-1 antitrypsin deficit)