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Recent studies have demonstrated that -syn aggregates bind to CL on mitochondrial membranes, driving mitochondrial damage, mitophagy, and the release of damage-associated molecular patterns (DAMPs) that potently activate microglia [29, 151, 201]

Embodiment 184 The method according to any one of embodiments 172- Embodiment 185 The method of embodiment 172, wherein said effector comprises a radionuclide
