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We used spectral imaging to compare GPX4 immunoreactivity in SN cells with presence or absence of neuromelanin

Dissociated hippocampal neurons transfected with mRFP-p-actin were stimulated for 5 days with sub-threshold concentrations of HGF and Dihexa (2.5 ng/ml + 10 ' 13 M, respectively), biologically active doses of HGF (10 ng ml), Dihexa or Nlel-AnglV (10 "12 M) or a combination of sub-threshold doses of 2.5 ng/ml HGF + 10 "12 M Dihexa or 2.5 ng/ml HGF + 10 "12 M Nlel-AnglV

Eating beforehand and staying hydrated can reduce the chance of symptoms

In addition, there is a higher intensity of CD38 expression (measured by flow cytometry) in the more aggressive multi-hit variants, which allows further differentiation of the diseases and the use of CD38 as a biomarker for early diagnosis [14]