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doi: 10.1179/135100005X21624

If this occurs, the drug should be discontinued

FIGURE 1 FIGURE 2 Oxidative stress effect on sepsis pathology Oxidative stress plays an essential role in the pathogenesis and progression of sepsis, primarily through the overproduction of ROS and impairment of antioxidant defence mechanisms

Interestingly, the SHMT2 HKO mice had three times more serum glycine levels than the control mice, which cannot solely be attributed to the expected decrease in glycine production
