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They can be engineered to carry exogenous proteins or nucleic acids, offering stability, safety, and a biomimetic nature 49

Autophagy, by contrast, is best framed as a compensatory quality-control program: although it can rise in parallel with inflammatory stress, its net role is often stabilizing because it removes damaged organelles/protein complexes and limits downstream inflammatory amplification

doi: 10.1111/j.1365-313X.2006.02973.x 65 van GelderenK.KangC.PaalmanR.KeuskampD.HayesS.PierikR

[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Prabhakar NR & Semenza GL Regulation of carotid body oxygen sensing by hypoxia-inducible factors