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Flak Trends in Endocrinology & Metabolism.2026;[Epub] CrossRef Type 2 Diabetes Mellitus as a Multisystem Disease: From Insulin Resistance to Organ CrosstalkA Narrative Review Hctor Fuentes-Barra, Ral Aguilera-Egua, Cherie Flores-Fernndez, Liss Angarita-Davila, Miguel Alarcn-Rivera Biomedicines.2026

Exposure to a number of stressors, including electrophiles, reactive oxidative species, heavy metals, and xenobiotics leads to conformational changes in Keap1, enabling stabilization and nuclear accumulation of Nrf2, where it coordinates the expression of multiple cellular defense enzymes, such as NAD(P)H:quinone oxidoreductase 1 (NQO1), heme oxygenase 1 (HO-1), and key components of the glutathione (GSH) and thioredoxin (TXN) antioxidant systems 2

The photothermal conversion efficiency was approximately 34%