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The FDA label includes a boxed warning regarding thyroid C-cell tumors observed in rodent studies, contraindicating use in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

Minoxidil comes with scalp irritation (usually traced back to the propylene glycol in the liquid) and a shedding phase in the first few weeks
doi:10.5056/jnm.2011.17.3.274 154

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