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10 El-Sakka observed 7.9% of 1,440 men being evaluated for ED with concomitant PD, 1 using strict PD diagnostic criteria including the presence of a palpable nodule or penile curvature observed after intracorporal injection of prostaglandin E1

Altered sciatic nerve fiber morphology and endoneural microvessels in mouse models relevant for obesity, peripheral diabetic polyneuropathy, and the metabolic syndrome

Conditions such as lupus, Guillain-Barre syndrome, rheumatoid arthritis, and Sjorgens syndrome can also result in nerve damage

Jensen et al., 2020), there are several intracellular mechanisms through which they could hypothetically impact signaling networks
