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[DOI] [PubMed] [Google Scholar] [96].Thust M, Schoning MJ, Schroth P, Malkoc U, Dicker CI, Steffen A, Kordos P, Luth H, Enzyme immobilisation on planar and porous silicon substrates for biosensor applications, J

For example, a study demonstrated dosedependent nephrotoxicity from CuONPs in rabbits, showing elevated kidney biomarkers (blood urea nitrogen, uric acid, creatinine) and tissue damage (hyperaemia, inflammation) after 15day exposure, highlighting potential toxicity concerns in this regard (Yegeubayeva et al

DNA Methylation Methylation has a vital role in managing normal biological activities in living systems (Esteller, 2007)

Thus, a potential cyto-toxicity of the incubation conditions can be excluded as reason for a release of the three Mrp1 substrates GSH, GSSG and GS-B from the cells into the media
