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In another in vivo study, coadministration of venlafaxine 150 mg/day, with a single 1-mg dose of risperidone, slightly inhibited its conversion of risperidone to 9-hydroxyrisperidone (9-OH-risperidone), which is partially metabolized by CYP-2D6
Neuronal-astrocyte metabolic association is essential for GSH synthesis, and it has been conducted on co-cultured astrocytes and neurons in which the presence of astrocytes leads to elevated GSH levels in neurons

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