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To understand if treatment with a GPX4 inhibitor was able to eliminate senescent cells in vivo, we treated mice transduced with an NRAS G12V -expressing transposon with RSL3 (Fig
The samples were treated with RIPA lysis buffer containing phosphatase inhibitors and protease inhibitors for 30 min, and then centrifuged at 12,000 r/min for 10 min to produce supernatants for the detection of MDA, SOD and GSH levels

An extract of irvingia seed has been shown to lower blood glucose and lipid levels, and reduce excess body weight (Ross 2011

Nutrition 20 , 2631 (2004)
