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Nrf2 and Oxidative Stress: A General Overview of Mechanisms and Implications in Human Disease 11(12)
[DOI] [PubMed] [Google Scholar] 145.Elia L., Contu R., Quintavalle M., Varrone F., Chimenti C., Russo M.A., Cimino V., De Marinis L., Frustaci A., Catalucci D., et al
Moreover, crizotinib can synergistically increase the MEK-inhibitor AZD6244-induced apoptosis and growth inhibition in vitro and in vivo in KRAS-mutated CRC cells (Van Schaeybroeck et al., 2014)
These include proteins involved in oxygen consumption, mitochondrial function, thermogenesis, and lipid and carbohydrate metabolism (Sorisky 2016)