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For instance, the red curve in Figure 2B predicts that a patient who switches from 1.7 mg q1wk to 2.4 mg q2wk would maintain 82% of their weight loss at 50% of the cost

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Manasanch EE, Mathur R, Lee HC, Weber DM, Patel KK, Thomas SK, Munoz SC, Morales de Partovi C, Claussen CM, Lin P, Amini B, Wang L, MA MCJ, Qing Y, Lei F, Baladandayuthapani V, Davis RE, Neelapu SS, and Orlowski RZ

The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis
