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Surface refined and cellular turnover accelerated

ILDs involve a complex interaction of inflammation, fibrosis, genetic predisposition, and environmental triggers, leading to gradual lung damage

For the pH-change experiments, 50 M PDIA6 and 4 mM CaCl 2 were mixed in 50 mM HEPES-NaOH at different pH values (pH 6.88.0) and PDIA6 droplets were observed after 10 min using a confocal microscope (LSM 800, Carl Zeiss)

3.1.2 EVs mediate cytochrome P450 enzyme synthesis and affect hormone levels Hyperandrogenism is closely associated with cytochromeP450(CYP450), particularly evident in the pathophysiology of PCOS (Zhai et al., 2023)