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260 Furthermore, Exos derived from human synovial mesenchymal stem cells overexpressing miR-140-5p were reported to enhance cartilage tissue regeneration and prevent knee osteoarthritis in a rat model

Hyperhomocysteinemia is recognized as an independent risk factor for artherosclerosis of the coronary, cerebral, and peripheral vasculature

Nonetheless, contemporary research is still nascent, necessitating more clinical studies to substantiate their efficacy, resolve concerns about strain selection and dose optimization, and facilitate the clinical implementation of GM-directed therapeutics for OP management (263)

This could provide an explanation for findings from previous studies which confirmed the capacity of A