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Bioorg Med Chem Lett 2007;17:4614
The Connection Between Oxidative Stress and Inflammation To answer the question of whether glutathione is anti-inflammatory, we must look at the cycle of oxidative stress
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It stimulates key dehydrogenases in the tricarboxylic acid (TCA) cycle, including pyruvate dehydrogenase, isocitrate dehydrogenase, and -ketoglutarate dehydrogenase, thereby increasing NADH production and enhancing electron flow through the respiratory chain
