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Taskran et al.s (2018) [24] protocol consisted of multiple intraperitoneal injections of vitamin B12 for a week before testing the animals with PTZ injections, while Filiz et al.s (2021) [1] protocol was to affect kindling procedures, which consisted of subthreshold convulsion doses of PTZ combined with vitamin B12 administration for about a month

Indeed, recent studies have shown that HIF-2 can be targeted by selective inhibitors and have indicated that these molecules effectively suppress cancer cell growth and tumor angiogenesis characteristics in ccRCC 79,80,81,82

Upon successful completion of the course, participants will receive certification in B12 injection administration