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Moreover, NO regulates the generation of ROS and reactive nitrogen species (RNS) by means of S-nitrosylation, a mechanism that chemically alters proteins, safeguarding them from oxidative harm

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Type I interferon-producing DCs and other cells that have taken up the vaccine-derived nucleic acids encoding the S protein can deliver both an antigenic and inflammatory signal to T cells in LNs draining the injection site

These compounds support long-term health by preventing chronic diseases, making them potentially beneficial for dogs with arthritis or other inflammatory conditions