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Intriguing questions need to be answered to increase our understanding: (1) Targeting mitochondria is a novel cancer treatment, but how can cancer cell mitochondria be selectively targeted to induce ferroptosis

Cancer 146 , 657663 (2020)

Role of Antioxidants during Chelation Induction of reactive oxygen species by metals and subsequent depletion of antioxidant cell defenses can result in disruption of the pro-oxidant/antioxidant balance in tissues [203]

Thereafter the same mutants were transformed with a copy of corresponding functional MG detoxification gene from Arabidopsis thaliana
