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Mice that overexpress Jak2VF in their erythroid lineage (VFEpoR mice) exhibit heightened necrosis in atherosclerotic plaque and erythrocytic ferroptosis, and VFEpoR increases erythrocyte lipid hydroperoxide and decreases antioxidant defense ability
doi: 10.1096/fj.07-9198com
In COPD, airway remodeling is primarily driven by a shift in arginine metabolism toward polyamine synthesis [10]
However, tetracycline, minocycline, dapsone, and topical corticosteroids are also mentioned as treatment options (234, 235, 237)
