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PMID: 174 LiDDZhouTGaoJWuGLYangGR

Human biomarker studies are the most direct evidence for clinical relevance but remain limited and sensitive to confounding by indication

But three things limit what these animal studies can tell us

The discovery of 5amino1mq (5amino1methylquinolinium) originated from intensive research into metabolic disorder regulation, centered on the inhibition of nicotinamide Nmethyltransferase (NNMT)
