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7cg and Extended Data Fig

Researchers have explored DSIP for possible effects on sleep regulation, stress response, pain signaling, endocrine function, and nervous system activity

Activated B cells become plasma cells and secrete antibodies involving in humoral immunity

ERK5 is a two-kinase transcription factor, and phosphorylation of ERK5 S496 directly inhibits NRF2 protein activity through SUMOylation modification at site 518, an inhibitory effect that can lead to inflammation and mitochondrial dysfunction in macrophages [133]
