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described two deaths due to VPA intoxication in their retrospective study of 316 patients in Iran ( Discussion In the case we present here, the assumed amount of ingested VPA was 56 g, which is, compared with other cases, at the upper end of the dose range in the reported cases

First, there is significant heterogeneity among the included studies in terms of design, patient populations, and outcomes, which complicates direct comparisons and limits the generalizability of the results

In previous reports, we observed molecular changes in SOD1 and inflammatory-related molecules in CSF only in the early phase of disease but not in the chronic phase

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