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Mechanistically, the study found that curcuminoids suppressed the expression of transcription factors specificity protein 1 (Sp1), Sp3, and Sp4, as well as several Sp-regulated oncogenic genes in SW480 cells
however, it does not contribute to the synthesis of proteins because it is a non-proteinogenic amino acid (Smith and Refsum 2021)
Iran J Public Health
Forcina and Dixon, 2019)
