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Benefits of topical application are that the skin attains far higher levels of each antioxidant than can be achieved by taking these vitamins orally and topical application arms the skin with a reservoir of antioxidants that cannot be washed or rubbed off, protecting the skin for several days after application

The same observations were made for treatment of GSSG in the presence of iron(II) complex ( 1 ) and iron(III) complex ( 3 ), both resulting in the immediate loss of GSSG signal intensity

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