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This energy supply supports excitability, biosynthesis of neurotransmitters, synaptic transmission and plasticity (reviewed by (Dienel, 2012))

Misbalanced CXCL12 and CCL5 Chemotactic Signals in Vitiligo Onset and Progression

Interestingly, although lipid peroxidation amplifies PARP-1 activation, inhibiting PARP-1 can significantly reduce lipid peroxidation and maintain mitochondrial integrity, underscoring the link between PARP-1 overactivation and oxidative damage in promoting parthanatos [142, 143]

Singh and Shekh-Ahmad, 2024
