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Oncotarget 8:6833868353 [DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted] Gilgun-Sherki Y, Rosenbaum Z, Melamed E, Offen D (2002) Antioxidant therapy in acute central nervous system injury, current state

2020 Oct;12(41):45753u201362

doi: 10.1016/j.celrep.2019.07.060 253 WyssM

In order to expand the toolbox of protocols for one-pot PROTAC synthesis using building blocks with different functional groups, Krumbs group published a new library of cereblon-based PROTACs targeting BRD4 protein via amide formation after a one-pot synthesis photoinduced C(sp 2 )C(sp 3 ) coupling (yields ranging from 7 to 93%)
