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Anderson P.H
Yes, noticeably so

Neuron 72:245256 Renton AE, Majounie E, Waite A et al (2011) A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

These effects were attributed to the increase in glycine concentrations in the CNS, which contribute to the modulation of pain through the activation of glycine receptors (Morita et al
