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Pregabalin and Amitriptyline Simpson et al
Ryan, M
The authors suggest that inhibition of FAO may lead to an overall decrease in cancer cell survival, while an increase in CPT1 activity, such as the PRL-mediated response, may provide a supportive environment for malignant cells 36
Given the prevalence of anxiety and depression in these patients, which ranges from 13 to 80% [118], antidepressants and antiepileptic drugs, which have been shown to be effective in the majority of patients, could also have a positive effect on pain symptoms and could be an indication for pharmacological treatment at the first approach
