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Priority was given to peer-reviewed human studies (including controlled and longitudinal designs), meta-analyses, and high-quality reviews
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Objective physiological data gathered from skin biopsies in this same study showed that after approximately six months of targeted supplementation with L-methylfolate, methylcobalamin, and pyridoxal 5'-phosphate, 73% of the patients demonstrated a measurable increase in calf epidermal nerve fiber density
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10.12659/MSM.916254 175 Xu YY.YangZ.DaiT.XueX.XiaD.FengZ.et al (2023)
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