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Description
Data indicate that OC cells release N-acetyl aspartate, which in conjunction with IL-10, synergistically induces the transformation of macrophages into M2-type TAMs that overexpress glutamine synthetase (103)

Activation of FXR by bile acid analogue or OCA drives -catenin activation in endothelial cells, and protect against gut vascular barrier disruption and NASH development [43]
It seems to work by promoting angiogenesis (the formation of new blood vessels) and modulating growth factors

3) Potential off-target effects: At high doses, they may disrupt normal lipid metabolism or mitochondrial function