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Description
Free ionic copper is toxic and tightly regulated in biological systems, but copper delivered as a peptide chelate bypasses those restrictions, allowing localized delivery to fibroblasts and keratinocytes without systemic copper overload

In conclusion, the results collected from this study demonstrate that the copper treatment can induce heart rate irregularity in zebrafish embryos, and this adverse effect can be nicely rescued by administrating recombinant GHK tripeptide

At the same time, the PG E2 receptor 2 subtype (PGE 2 -EP2) localizes in apoptotic oligodendrocytes in the cortex, suggesting an involvement of PG in oligodendrocyte death in the cuprizone model

H.CoultonL.ShaughnessyJ
