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Description
This reaction simultaneously depletes two critically important metabolic cofactors: SAM (the universal methyl donor for hundreds of epigenetic and biosynthetic reactions) and nicotinamide (the precursor for NAD+ biosynthesis via the salvage pathway)
This allows tissue recovery and reduces the buildup of irritation
It is characterised by inflammation and atrophy of the gastric mucosa resulting in reduced production of intrinsic factor and gastric acid
Ultrasonography (USG) showed normal liver and spleen and kidneys
