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It is noteworthy that an intriguing animal study demonstrated that CGRP preferentially activates and sensitizes trigeminal nociceptors in the dura of female mice, but not male mice [111]

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According to NHANES data, PID affects approximately 2.5 million women of reproductive age in the United States, and while antibiotic treatment can alleviate symptoms, poor obstetric outcomes and high recurrence rates persist

Thus, it can be said that the development of cancer is not only due to the type of habit that patients have but depends on interaction between the metabolites and the genes that detoxify these metabolites/carcinogens