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Similarly, 600 mg LA/day, i.v., for 3 weeks showed no adverse effects [58], and 1800 mg LA/day, p.o., for 6 months was also safe [59]
Released AIF translocates to the nucleus where it promotes chromatin condensation and DNA fragmentation
Human clinical trial data remain sparse but are accumulating
The neurological symptoms often develop insidiously over months or years, and may appear before haematological abnormalities become evident on routine blood tests
