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Description
ROS also played an important role in the release of cytochrome c and other pro-apoptotic proteins, which can trigger caspase activation and apoptosis
The combination of cetuximab and -elemene not only promotes ferroptosis in CRC cells, but also promotes the expression of E-cadherin (epithelial marker) while reducing the expression of mesenchymal markers such as snail, vimentin, N-cadherin, slug, and MMP-9
The supernatant was then removed, and cells grown in MEM + 2% NCS containing carboxy-methylcellulose for 4 days
Nature, 540: 276-279
