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A 2025 intravenous safety study involving two healthy adults found infusions up to 20 mg well tolerated, with no adverse events or clinically meaningful changes in vital signs or laboratory biomarkers

[DOI] [PubMed] [Google Scholar] 77.Canadian Agency for Drugs and Technologies in Health
Biochimie 144:122133

For people without a deficiency, benefits may be subtle or minimal
