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[4] Receptor Grade IGF-1 LR3 and Insulin-Like Growth Factor Receptor Interactions Naturally produced IGF-1 hormones interact with at least two cell surface receptors: the IGF-1 receptor (IGF-1R) and the insulin receptor

[DOI] [PubMed] [Google Scholar] 231.Schrch CM et al

As of now, Opdivo has obtained 29 indications in 11 types of tumors

BMC cancer 13 , 462