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Another trial showed broccoli sprout extract increased NQO1 mRNA in buccal cells, suggesting a chemopreventive role against oral cancer (16)

Huang C-H Unexpected Role of Activated Carbon in Promoting Transformation of Secondary Amines to N-Nitrosamines

Oxidative stress is counteracted by a number of genes regulated by the nuclear transcription factor erythroid-derived 2-like 2 (NRF2), encoded by the NFE2L2 gene, which initiates antioxidant responses and detoxifies xenobiotics (Figure 7B)
