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Description
By inhibiting autophagy and inducing mitochondrial ROS, TMAO activates NLRP3 inflammasome, leading to the release and pyroptosis of IL-1/IL-18 dependent on caspase-1 in colon epithelium, which is a hallmark of IBD severity

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Elevated levels of trimethylamine oxide in muscles of deep-sea gadiform teleosts: a high-pressure adaptation
