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Description
(6) Homocysteine also rises with low B12, though it is less specific because folate status and kidney function move it as well

This research explores a novel therapeutic avenue by targeting the brains renin-angiotensin system (RAS) and its interaction with the hepatocyte growth factor (HGF)/c-Met receptor system [2]
Using it for human self-administration occupies a legal gray area

The biological rationale is sound