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This innovative approach has been shown to enhance the absorption and subsequent bioavailability of a variety of supplemental nutrients, such as vitamin D3, iron, and magnesium, suggesting that it could similarly improve the efficacy of oral B12 supplementation (2529)

I'm not a medical professional so I can't advise you but just relating my personal experience with this is that 31 gauge can work just fine

However, evidence from research studies suggests that GLP-1 analogs may also reduce gastric acid secretion, which can impair the conversion of dietary B12 into its absorbable form and decrease binding to intrinsic factor, both of which are necessary for proper absorption